Club president Mohan Nanayakkara said his group was formed on April 28, 1964, to continue the assistance the Lions Club of Epping-Eastwood had already been giving to Inala.
Ianala chief executive Tony Anderson said what the Lions do for them could fill a book.
"They help with gardening, cleaning . . . they come to nearly all the Inala fairs, they run the chocolate wheel, they barbecue for us, they volunteer at our golf days," Mr Anderson said.
More than 120 people gathered at the Madison Centre, Dural earlier this month to celebrate the club's golden anniversary.
The club held its first charter dinner in August 1964.
Professor Jennifer Byrne, head of the Cancer Research Unit at The Children's Hospital at Westmead, was presented with a cheque for $11,000.
Members also paid tribute to the work of the club's charter president Donald Moore, a former councillor who was a club member for 39 years until his death in 2003.
Since its inception, the Lions club has raised more than $2 million in cash and in kind for community groups, and offered assistance in more than 1600 projects.
"We provide medicines and medical assistance at three medical camps in Sri Lanka, and we collect used spectacles and send them to Sri Lanka," Mr Nanayakkara, of Cherrybrook, said.
He joined the Lions Club of Wattala in Sri Lanka first and decided he'd like to continue their good work when he moved to Australia.
■ Details: Mohan, 0400 024 052.